Family & Cosmetic Dentistry in Florence, Mississippi

A Comfortable Experience.

A Confident Smile.

At Cole Family Dentistry in Florence, Mississippi, we provide preventive, cosmetic and restorative dental care with a gentle, welcoming approach designed to help patients of all ages feel at ease.

Preventive First

Cleanings and checkups

Smile Enhancements

Whitening and cosmetic care

Family Dentistry

Care for patients of all ages

Florence, Mississippi

2614 Highway 49 South

Services that help you

Maintain. Enhance. Love Your Smile.

Healthy smiles start with preventive care. Regular cleanings and checkups help protect your oral health, while whitening, Invisalign®, cosmetic bonding and restorative dentistry give you options when you want to enhance or restore your smile.

Dental Cleanings

Routine professional cleanings and checkups to help protect your teeth and gums.

Teeth Whitening

Professional Opalescence whitening options for a noticeably brighter smile.

Cosmetic Dentistry

Tooth-colored bonding and cosmetic solutions for chips, discoloration and minor spacing concerns.

Clear Aligners

Invisalign® and SureSmile® clear aligners that gradually straighten teeth without traditional brackets and wires.

Family Dentistry

Preventive and restorative dental care for children, adults and families.

Meet Dr. Melissa Cole

Gentle Care. Honest Dentistry. A Smile You’ll Love.

Dr. Cole and her team believe dental care should feel different: welcoming, clear and centered around the person in the chair. The goal is excellent dentistry without losing the small-town warmth that helps patients feel at ease.

Your Comfort Matters

A Calmer, More Welcoming Dental Experience.

We understand that visiting the dentist can feel stressful for some patients. Our team takes time to listen, explain what to expect and help you feel comfortable throughout your visit. If you experience dental anxiety or sensitivity, let us know so we can talk through options that may make your appointment easier.

What patients notice

Loved for the Way We Care.

Patients consistently mention the friendly team, welcoming environment and the feeling that their comfort matters.

presley price

2 days ago

The nicest staff!

Ethan Miller

2 weeks ago

Had a great experience at this office not once, not twice, but three times. Dr. Cole was amazing and took care of me the whole time and did a great job on my teeth. Madison was awesome and let me talk her head off and was very fun to talk to. Mandy is amazing and did a great job of scheduling me to be able to come up there. Nothing but great things to say.

Chase Covington

2 weeks ago

I had a great experience at this office. Dr. Cole was so kind and took the time to walk me through everything she was doing, which really put me at ease. Mandy was incredibly helpful with the paperwork and made the whole check-in process smooth. Madison was gentle and kind throughout the entire visit. I felt well taken care of from start to finish and would definitely recommend them.

Brittany Mckinley

4 weeks ago

Very sweet people !!! Does a wonderful job !!

Teneka Lewis

2 months ago

Cole Family Dentistry is a hidden gem! I made a decision to start supporting businesses in Florence, since this is where we live. From the receptionist to the assistant to Mrs.Cole! They were all welcoming and nice. I have 3 kids that absolutely love them. I thought my 2 year old would be a little scared to go back but he sure wasn’t. That should tell you how family oriented and welcoming they are. Thank you all so much for your professionalism and kindness!

Jason Lawrence

2 months ago

If you are looking for a professional staff, that is all about treating you like a person instead of a patient and remembering certain particulars about what makes you feel comfortable in a dental setting from the doctor to the dental assistant to the front staff Dr Melissa Cole DMD is the place to go. Her staff is wonderful. I have been with her for approximately 3 to 5 years and I have some special issues that they always remember to take care of and it’s already done before I even walk into the treatment room the prices are extremely reasonable and Dr Cole and her staff make sure that you have all the options that are available and roundabout how much it will cost. Dr. Cole is extremely low pressure and she is not a sales person. She is here to take care of what you came in for make recommendations with no pressure and carry on about her dental duties highly recommended.

Jessica Honea

3 months ago

My boys have been seeing Dr Cole and her staff since they were toddlers! They are 13 and 8 now!! The staff have been nothing short of outstanding! They are patient with insurance issues! They are understanding with accidental missed appointments! The boys get great cleanings and checkups and receive good reports everytime! Neither one of my children have had a cavity and Im positive its because of the great care they receive every 6 months and the great encouragement they give my children! Its a great Dentist for the whole family! You will not be disappointed!

Jazmine Hatchett

4 months ago

Today was my first visit. I found them on Google. If I could give this dentistry 10 stars, I would, 10 times over. The entire staff was so pleasant and welcoming. Smiles on every face! Literally the best team of ladies I’ve ever encountered. Dr. Cole was so sweet and gentle with me and the process. I love this place already!

Brian Young

6 months ago

I lived with a lifelong fear of the dentist due to a bad experience as a child. The ladies at Cole are gentle with me and make me feel comfortable. After seeing them for around 7 years now I no longer mind visiting the dentist. They are very kind people and the atmosphere is very relaxed (which is big for me being an anxious person). If you haven’t visited the dentist due to fear or dislike of your current dentist, I would encourage you to give them a try!! I don’t think you will be disappointed!

Convenient care

Visit Us in Florence.

Find Cole Family Dentistry at 2614 Highway 49 South in Florence, Mississippi. Call our office or use the online scheduling link to request an appointment.

Florence, Mississippi

Florence Office

2614 Highway 49 South
Florence, MS 39073